Marianne De Paepe

This study shows that bacteriophage T4 uses two glucosyltransferases to modify its DNA, helping it evade bacterial defense systems, with redundancy providing an evolutionary advantage.

This study shows that Campylobacter jejuni Bf extracellular vesicles help the bacteria adapt and survive under combined thermal and oxidative stress by altering membrane composition and increasing toxicity to epithelial cells.

The paper investigates phage translocation across the intestinal barrier in health and Crohn's disease, finding increased phage presence in blood samples from CD patients.

This study measures the mutation rate of phage lambda and finds it is higher than its host E. coli but not significantly increased by MMR inactivation.

This paper describes a CRISPR-Cas13b-based method to edit the T4 bacteriophage genome, enabling gene deletions, mutations, and fluorescent protein insertion for studying phage biology.

The paper compares DNA preparation methods for virome sequencing, finding that T7 DNA polymerase treatment improves representation of both ssDNA and dsDNA viruses compared to MDA or xGen kit.

The paper studies the blood virome in healthy individuals and Crohn's disease patients, finding distinct viral communities associated with the disease.