Author

Marlène Z. Lacroix

École Nationale Vétérinaire de ToulouseORCID 0000-0002-6981-8340Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Agnès JaminiD· 1 shared Anne LespineiD· 1 shared Barbara KubíčkováiD· 1 shared Clara BlancfuneyiD· 1 shared Daniel ZalkoiD· 1 shared Élise CourtotiD· 1 shared Elodie PersoniD· 1 shared Eva Guchen· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Agnès JaminORCID

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2 papers

Recent·Most cited

Chemical augmentation of the validated HepaRGTM CYP enzyme induction test method Part 1: The Goliath two laboratory study

Miriam Naomi Jacobs, Barbara Kubíčková, Elodie Person, Jorke Harmen Kamstra, Nicolas J. Cabaton, Sebastian Hoffmann, Agnès Jamin, Marlène Z. Lacroix, Juliette Legler, Vesna Munić Kos, Sandra M. Nijmeijer, Theo L. Sinnige, Laurie Urien, Daniel Zalko

This paper validates the HepaRG CYP enzyme induction test method for pharmaceutical and non-pharmaceutical chemicals, showing good reproducibility for pharmaceuticals but less consistency for non-pharmaceuticals.

bioRxiv · Jun 20, 2026 · PreprintPharmacology & Toxicology

Critical Role of P-Glycoprotein-9 in Ivermectin Tolerance in Nematodes

Clara Blancfuney, Eva Guchen, Marie Garcia, Julien Faccini, Jean‐François Sutra, Felipe Ramon‐Portugal, Élise Courtot, Marlène Z. Lacroix, Roger K. Prichard, Anne Lespine, Mélanie Alberich

This study identifies P-glycoprotein-9 as a key mediator of ivermectin resistance in nematodes by showing its role in drug efflux and demonstrating functional conservation across species.

PLoS Pathogens · Mar 23, 2026Peer-reviewedMicrobiology