Author

Caden J. Martin

The Ohio State UniversityORCID 0000-0002-6982-5049Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Approach:statistical model· 1

Frequent Co-Authors

Mark R. ParthuniD· 3 shared Prabakaran NagarajaniD· 3 shared Elizabeth A. OseriD· 2 shared Liudmila V. PopovaiD· 2 shared Andrea R. KelleriD· 1 shared Benjamin D. SunkeliD· 1 shared Benjamin Z. StantoniD· 1 shared Callie M. Lovejoy· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersBiochemistry

Mark R. ParthunORCID

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3 papers

Recent·Most cited

Hat1 Orchestrates Heterochromatin Inheritance by Regulating Localization of H3K9 Methyltransferases

Caden J. Martin, Liudmila V. Popova, Prabakaran Nagarajan, Elizabeth A. Oser, Callie M. Lovejoy, Benjamin D. Sunkel, Benjamin Z. Stanton, Michael A. Freitas, Mark R. Parthun

This study shows Hat1 regulates H3K9 methylation and HMT localization in LADs, affecting heterochromatin structure and inheritance in mouse cells.

bioRxiv · Mar 23, 2026 · PreprintBiochemistry

HAT1 Regulates Intestinal Stem Cell Proliferation and Differentiation

Prabakaran Nagarajan, Caden J. Martin, Andrea R. Keller, Kubra B. Akkaya-Colak, Maria H. Festing, Maria M. Mihaylova, Mark R. Parthun

This study shows HAT1 is essential for intestinal stem cell proliferation, differentiation, and chromatin structure regulation in intestinal crypts.

bioRxiv · Mar 18, 2026 · PreprintCell Biology

Distinct Classes of Lamin-Associated Domains are Defined by Differential Patterns of Repressive Histone Methylation

Caden J. Martin, Prabakaran Nagarajan, Elizabeth A. Oser, Liudmila V. Popova, Mark R. Parthun

The paper identifies three distinct LAD classes based on histone modification patterns in mouse MEF cells, revealing heterochromatin-specific regulatory roles.

bioRxiv · Dec 20, 2024 · PreprintGenomics