Author

Maria H. Festing

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research InstituteORCID 0009-0004-9931-7602Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:development & morphogenesis· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Andrea R. KelleriD· 3 shared Kubra B. Akkaya-Colak· 3 shared Maria M. MihaylovaiD· 3 shared Ayobami Adeniyi· 2 shared James SledzionaiD· 2 shared Khushboo GuptaiD· 2 shared Maciej PietrzakiD· 2 shared Patrick Stevens· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersPhysiology

Andrea R. KellerORCID

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Author profile →

3 papers

Recent·Most cited

HAT1 Regulates Intestinal Stem Cell Proliferation and Differentiation

Prabakaran Nagarajan, Caden J. Martin, Andrea R. Keller, Kubra B. Akkaya-Colak, Maria H. Festing, Maria M. Mihaylova, Mark R. Parthun

This study shows HAT1 is essential for intestinal stem cell proliferation, differentiation, and chromatin structure regulation in intestinal crypts.

bioRxiv · Mar 18, 2026 · PreprintCell Biology

Gasdermin C links nutrient and immune signaling to protist-induced type 2 immunity and intestinal repair

Andrea R. Keller, Ayobami Adeniyi, Kubra B. Akkaya-Colak, Maria H. Festing, Andrew Schwieters, Rathan Kumar, James Sledziona, Khushboo Gupta, Patrick Stevens, Maciej Pietrzak, Vincenzo Coppola, Parvathi Ranganathan, Brian Ahmer, Adriana Forero, Sue E. Knoblaugh, Maria M. Mihaylova

bioRxiv · Sep 24, 2025 · PreprintPhysiology

Stearoyl-CoA Desaturases regulate stem and progenitor cell metabolism and function in response to nutrient abundance

Kubra B. Akkaya-Colak, Andrea R. Keller, Maria H. Festing, Khushboo Gupta, James Sledziona, Ayobami Adeniyi, Omar West, Patrick Stevens, Maciej Pietrzak, Sue E. Knoblaugh, Helaina Walesewicz, Dominique A. Baldwin, Judith Simcox, James Mukasa Ntambi, Steven K. Clinton, Maria M. Mihaylova

This study shows that Stearoyl-CoA Desaturases (SCDs) regulate intestinal stem and progenitor cell metabolism and function in response to nutrient abundance, affecting tissue homeostasis and regeneration.

bioRxiv · Sep 17, 2025 · PreprintPhysiology