NeuroscienceBrain CommunicationsPeer-reviewed
Altered skeletal muscle glucose-fatty acid flux in amyotrophic lateral sclerosis (ALS)
Frederik J. Steyn, Rui Li, Siobhan E. Kirk…·Shyuan Thieu Ngo
This study investigates altered glucose-fatty acid flux in ALS using mouse models and patient-derived myotubes, finding increased fatty acid oxidation linked to slower disease progression but with metabolic heterogeneity across patients.