NeuroscienceNeurobiology of DiseasePeer-reviewed
Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression
Júlia Canet-Pons, Nesli-Ece Şen, Aleksandar Arsović…·Georg W. J. Auburger
This study examines an SCA2 mouse model to identify molecular mechanisms of spinal cord pathology, finding progressive TDP43 aggregation and cholesterol biosynthesis suppression.
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