Allergic airway inflammation protects against SARS-CoV-2 and MERS-CoV disease but promotes fatal SARS-CoV-1 immunopathology
Jeremy Ardanuy, Grace Garrett, Carly Dillen…·Matthew B. Frieman
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University of Maryland, BaltimoreORCID 0000-0002-6993-5838Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Jeremy Ardanuy, Grace Garrett, Carly Dillen…·Matthew B. Frieman
Louis J. Taylor, Thiagarajan Venkataraman, Matthew B. Frieman
The paper develops a phage display library, C-Spike, to profile antibody responses to coronavirus spike proteins and identifies binding motifs using alanine-scanned peptides.
Stuart M. Weston, Lauren Baracco, Louis J. Taylor…·Matthew B. Frieman
This paper identifies the SKI complex as a broad-spectrum antiviral target, showing that UMB18 increases cellular cholesterol via the mevalonate pathway to inhibit viral replication.
Erik Clarke, Louis J. Taylor, Chunyu Zhao…·Kyle L. Bittinger
Sunbeam is a modular pipeline for metagenomic analysis that standardizes preprocessing and removes low-complexity reads, enabling reproducible and extensible workflows.