Dillon Cislo

This paper introduces a computational framework to reconstruct developmental landscapes from single-cell data, revealing morphogen-dependent cell fate transitions in neural progenitors.

TubULAR tracks tissue deformations by mapping 3D surfaces to 2D with minimal motion, enabling analysis of collective tissue dynamics in Drosophila and zebrafish.

The paper shows how floorplate organiser forms autonomously in neural tube organoids through BMP-mediated cluster competition and FOXA2 dynamics.

The paper shows cell divisions drive fourfold orientationally ordered tissue phases in Parhyale hawaiensis embryos through active defect climb mechanisms.

The paper studies how multi-layer tissue interactions drive organ shape changes in Drosophila embryos, identifying calcium-patterned muscle contractions as a key mechanism.