Author

Mikel D. Haggadone

University of PennsylvaniaORCID 0000-0002-7001-9132Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Sunny ShiniD· 2 shared Víctor R. Vázquez MarreroiD· 2 shared Aaron Wu· 1 shared Allyson Lu· 1 shared Aoife O’FarrelliD· 1 shared Arjun RajiD· 1 shared Brian P. GoldspieliD· 1 shared Clémence QueriaultiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersImmunology

Sunny ShinORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 20, 2026

Environmental Amino Acid Sensing Regulates the Rate of ASC Translation and NLRP3 Inflammasome Assembly

Mikel D. Haggadone, Brian P. Goldspiel, Aoife O’Farrell…·Will Bailis

This study shows that environmental branched-chain amino acids regulate ASC translation and NLRP3 inflammasome assembly through mTOR-dependent translational bursting.

1 citation

mousehuman

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ImmunologyInfection and ImmunityPeer-reviewedJun 5, 2025

GM-CSF engages multiple signaling pathways to enhance pro-inflammatory cytokine responses in human monocytes during Legionella infection

Víctor R. Vázquez Marrero, Madison Dresler, Mikel D. Haggadone…·Sunny Shin

This study shows GM-CSF enhances cytokine production in human monocytes during Legionella infection through multiple signaling pathways.

3 citations

humanexperimental assay

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