Author

Ruaidhrí P. Jackson

Harvard UniversityORCID 0000-0002-7002-0010Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Alec J. WalkeriD· 1 shared Ariel JaffeiD· 1 shared Beth StevensiD· 1 shared Christophe O. BenoistiD· 1 shared Diane J. MathisiD· 1 shared Elisa CintadoiD· 1 shared Esen SefikiD· 1 shared Felipe Almeida Pinho-RibeiroiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Alec J. WalkerORCID

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2 papers

Recent·Most cited

The meninges host a unique compartment of regulatory T cells that bulwarks adult hippocampal neurogenesis

Miguel Marin-Rodero, Elisa Cintado, Alec J. Walker, Teshika Jayewickreme, Felipe Almeida Pinho-Ribeiro, Quentin Richardson, Ruaidhrí P. Jackson, Isaac M. Chiu, Christophe O. Benoist, Beth Stevens, José Luís Trejo, Diane J. Mathis

The paper identifies a unique population of regulatory T cells in the murine meninges that maintain brain homeostasis by suppressing interferon-gamma-producing lymphocytes and preventing hippocampal damage.

Science Immunology · Jan 28, 2025Peer-reviewedImmunology

Detection of differentially abundant cell subpopulations discriminates biological states in scRNA-seq data

Jun Zhao, Ariel Jaffe, Henry Li, Ofir Lindenbaum, Esen Sefik, Ruaidhrí P. Jackson, Xiuyuan Cheng, Richard Anthony Flavell, Yuval Kluger

DA-seq identifies differentially abundant cell subpopulations between biological states in scRNA-seq data, revealing both known and novel subpopulations with biological insights.

bioRxiv · Oct 1, 2020 · PreprintBioinformatics