Multiplexed and reproducible high content screening of live and fixed cells using the Dye Drop method
Caitlin E. Mills, Kartik Subramanian, Marc A. Hafner, Mario Niepel, Luca Gerosa, Mirra Chung, Chiara Victor, Benjamin L. Gaudio, Clarence Yapp, Ajit J. Nirmal, Nicholas A. Clark, Peter Karl Sorger
The paper introduces a method called Dye Drop for high-throughput single-cell assays in 384-well plates, enabling detailed dose-response analysis of small molecules in breast cancer cell lines.
Nature Communications · Nov 14, 2022Peer-reviewedSystems Biology