Author

Diego A. Figueroa

Fundación Ciencia and VidaORCID 0000-0002-7003-9205Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Álvaro LladseriD· 2 shared Andrés Hernández‐OliverasiD· 2 shared Felipe Gálvez‐CancinoiD· 2 shared Sofía HidalgoiD· 2 shared Vincenzo BorgnaiD· 2 shared Camelia RadulescuiD· 1 shared Catalina Bustamante· 1 shared Christine SedlikiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Álvaro LladserORCID

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3 papers

Recent·Most cited

The differentiation and functional landscape of tumor-resident CD8⁺ T cells shapes immunity and clinical outcomes in clear cell renal cell carcinoma

Sofía Hidalgo, Andrés Hernández‐Oliveras, Jimena Tosello Boari, Javiera Reyes-Alvarez, Sergio Herńandez-Galaz, Catalina Bustamante, Ernesto López, Yoann Missolo-Koussou, Wilfrid Richer, Vincenzo Benedetti, Farides Saavedra, Marco Fraga, Eduardo Roa, Diego A. Figueroa, Christine Sedlik, , Álvaro Lladser

The paper identifies three CD8+ T cell subsets in ccRCC and links their differentiation states to clinical outcomes.

bioRxiv · Mar 15, 2026 · PreprintImmunology

The Diverse Phenotypic and Mutational Landscape Induced by Fluoroquinolone Treatment

Sayed Golam Mohiuddin, Pouria Kavousi, Diego A. Figueroa, Sreyashi Ghosh, Mehmet A. Orman

This study examines how fluoroquinolone treatment induces diverse phenotypic and mutational changes in E. coli, showing that tolerance and resistance can evolve independently with varied fitness effects.

mSystems · Jul 31, 2025Peer-reviewedMicrobiology

Long-term efficacy of adoptive cell therapy is determined by host CD8+ T cells and undermined by lymphodepleting preconditioning

Diego A. Figueroa, Juan Pablo Vega, Andrés Hernández‐Oliveras, Felipe Gálvez‐Cancino, Felipe Ardiles, Felipe Flores, Sofía Hidalgo, Ximena López, Hugo González, Fabiola Osorio, Vincenzo Borgna, Álvaro Lladser

This study shows that host CD8+ T cells enhance adoptive cell therapy (ACT) efficacy against melanoma, while lymphodepleting preconditioning reduces long-term effectiveness by impairing host immunity.

bioRxiv · May 16, 2024 · PreprintImmunology