Author

Isabelle Léger‐Silvestre

Centre National de la Recherche ScientifiqueORCID 0000-0002-7030-5593Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:yeast· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Olivier GadaliD· 2 shared Adrien ChauvieriD· 1 shared Anthony K. HenrasiD· 1 shared Benjamin AlbertiD· 1 shared Bruno R.S. Queiroz· 1 shared Carla Columbano OliveiraiD· 1 shared Carlos Fernández‐TorneroiD· 1 shared Christophe DeziD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Olivier GadalORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular Biology of the CellPeer-reviewedApr 23, 2025

New Insights into nuclear import and nucleolar localization of yeast RNA exosome subunits

Valdir Gomes Neto, Leidy Paola Páez Cepeda, Bruno R.S. Queiroz…·Carla Columbano Oliveira

This study characterizes the subcellular localization and nuclear import mechanisms of yeast RNA exosome subunits, revealing their nucleolar distribution and interactions with importins and cofactors.

3 citations

yeastproteomics

Molecular BiologyPLoS GeneticsPeer-reviewedMay 28, 2019

Genetic analyses led to the discovery of a super-active mutant of the RNA polymerase I

Tommy Darrière, Michael Pilsl, Marie-Kerguelen Sarthou…·Olivier Gadal

The paper identifies mutations in RNA polymerase I that enhance its activity, leading to increased rRNA production in yeast.

34 citations

yeaststatistical model