Carlos Fernández‐Tornero

This study uses cryo-EM to reveal a two-step mechanism of RNA polymerase I stalling at abasic DNA lesions, distinct from other lesion types.

This study identifies phosphorylation sites in Rpb4 that regulate Rpb4/7 stoichiometry and gene expression in yeast.

This study presents the cryo-EM structure of trypanosome 3-methylcrotonyl-CoA carboxylase, revealing its mechanism and dynamic features relevant to drug discovery.

This study determines the structural basis of Ty1 integrase interaction with RNA polymerase III, revealing key residues and conformational changes that facilitate targeted DNA integration.

The paper identifies mutations in RNA polymerase I that enhance its activity, leading to increased rRNA production in yeast.