NeurosciencebioRxivPreprint
Upregulation of FasII underlies synergistic neuropathological and behavioral defects in a Drosophila model of myotonic dystrophy
Alex Chun Koon, Ka Yee Winnie Yeung, Lok I Leong…·Ho Yin Edwin Chan
This study identifies FasII upregulation as a key factor in DM1 neuropathology using a Drosophila model, showing that manipulating FasII isoforms can rescue synaptic and behavioral defects.
DOI 10.1101/2024.05.26.595976