Gut microbe-derived short-chain fatty acids regulate joint inflammation and activation of infiltrating and resident myeloid cells after alphavirus infection
Fang R. Zhao, Maksim Kleverov, Emma S. Winkler, Russell B. Williams, Hana Jáňová, Lindsay Droit, Leran Wang, Tingting Li, Leah Heath, Ana Jung, Matthias Mack, Megan T. Baldridge, Thaddeus S. Stappenbeck, Larissa B. Thackray, Chyi‐Song Hsieh, , Michael Diamond
This study shows that gut microbe-derived short-chain fatty acids reduce joint inflammation after alphavirus infection by modulating immune cell activity.
bioRxiv · Dec 3, 2025 · PreprintImmunology