Massimo Delledonne

Photoprotection comes at a cost: non-photochemical quenching shapes growthproductivity trade-offs in Haematococcus lacustris

This study shows that enhanced non-photochemical quenching (NPQ) in Haematococcus lacustris improves high-light tolerance under carbon limitation but reduces growth and astaxanthin productivity under high CO2 conditions.

Long-read cross-platform validation reveals novel repeat features in myotonic dystrophy type 2

The paper validates long-read sequencing methods for analyzing repeat expansions in DM2, identifying new repeat motifs and improving bioinformatic workflows.

On-site microbial community analysis in rivers: integrating autonomous sampling with a portable sequencing workflow

The paper develops a portable sequencing workflow for in situ microbial community analysis in rivers, combining autonomous sampling with field and lab sequencing to reduce costs and improve temporal resolution.

The unexplored diversity of wild lupins provides rich genomic resources and insights into lupin evolution

This study sequenced two wild lupin species to explore their genomic diversity and evolutionary insights, revealing gene family expansions linked to seed size and adaptation.

Landscape genomics highlights the adaptive evolution of chickpea across the Silks Roads

The paper identifies genotype-environment associations and adaptive variation in chickpea along historical Silk Road routes, highlighting genes related to heat and drought tolerance.

The evolutionary history of the common bean (Phaseolus vulgaris) revealed by chloroplast and nuclear genomes.

This study uses chloroplast and nuclear genomes to trace the evolutionary history of common beans, supporting a Mesoamerican origin and rejecting a new species classification.

CRISPR/Cas9-based repeat depletion for the high-throughput genotyping of complex plant genomes

This paper uses CRISPR/Cas9 to deplete repetitive DNA in lentil genomes, improving genotyping accuracy and efficiency by focusing sequencing on single-copy regions.

Characterization of full-length CNBP expanded alleles in myotonic dystrophy type 2 patients by Cas9-mediated enrichment and nanopore sequencing

This study characterizes full-length CNBP repeat expansions in DM2 patients using Cas9-mediated nanopore sequencing, revealing novel repeat patterns and mosaicism.

Genomic structural variation in Nebbiolo grapevines at the individual, clonal and cultivar levels

The paper analyzes structural variants in Nebbiolo grapevines across individual, clonal, and cultivar levels using long-read and optical mapping data.

Whole-exome sequencing of the mummified remains of Cangrande della Scala (1291-1329 CE) indicates the first known case of late-onset Pompe disease

The paper performs whole-exome sequencing on mummified remains to identify a genetic mutation associated with late-onset Pompe disease in a historical figure.

Enhanced targeted resequencing by optimizing the combination of enrichment technology and DNA fragment length

The paper evaluates how DNA fragment length and enrichment technology affect genotypability in whole-exome sequencing, finding that longer fragments improve callable bases and genotypability across different platforms.

Pod indehiscence in common bean is associated to the fine regulation of PvMYB26 and a non-functional abscission layer

The paper identifies PvMYB26 as a candidate gene for pod indehiscence in common bean, linking its fine regulation to the absence of a functional abscission layer.

A rapid and accurate MinION-based workflow for tracking species biodiversity in the field

This paper introduces a portable workflow for on-site DNA barcoding using MinION sequencing and ONTrack pipeline, achieving high accuracy and low computational demand for field biodiversity tracking.