Giuseppe Novelli

The paper validates long-read sequencing methods for analyzing repeat expansions in DM2, identifying new repeat motifs and improving bioinformatic workflows.

The paper identifies rare loss-of-function variants in type I IFN immunity genes associated with severe COVID-19, particularly in younger patients with recessive inheritance.

This study characterizes full-length CNBP repeat expansions in DM2 patients using Cas9-mediated nanopore sequencing, revealing novel repeat patterns and mosaicism.

This paper describes the engineering of peptide-antibody fusions using phage display to enhance neutralization potency and breadth against SARS-CoV-2 variants.

This study compares genomic variations in immune-related genes between Qatari and Italian populations to identify differences in selective pressures.

This paper develops tetravalent SARS-CoV-2 neutralizing antibodies that are more potent and resistant to escape mutations than bivalent versions.

The paper analyzes ACE2 genetic variants in 99 COVID-19 patients using whole-exome sequencing and finds no allelic association with disease severity or sex bias.