Author

Travis Maxfield

University of North Carolina at Chapel HillORCID 0000-0002-7105-0246Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Brandon NovyiD· 2 shared Devan J. ShelliD· 2 shared Eric M. MerteniD· 2 shared Ivanna ZhilinskayaiD· 2 shared James WellnitziD· 2 shared Kenneth H. PearceiD· 2 shared Konstantin I. PopoviD· 2 shared P. Brian Hardy· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Brandon NovyORCID

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2 papers

Recent·Most cited

BioinformaticsJournal of CheminformaticsPeer-reviewedSep 4, 2026

Open-Source DNA-Encoded Library Package for Design, Decoding, and Analysis: DELi

James Wellnitz, Brandon Novy, Shu-Hang Lin…·Konstantin I. Popov

DELi is an open-source platform for DNA-encoded library design, decoding, and analysis, demonstrating its effectiveness through the identification of a BRD4 binder.

3 citationstop 2%

DNA methylationexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintSep 30, 2025

Expansion of DNA-Encoded Library Hits Using Generative Chemistry and Ultra-Large Compound Catalogs

Brandon Novy, Shu-Hang Lin, Devan J. Shell…·Konstantin I. Popov

This paper combines DNA-encoded libraries with generative AI to expand hit compounds, finding AI-selected hits show better drug-likeness and diversity than initial DEL hits.

DOI 10.1101/2025.09.30.679600

deep learningdrug response / drug discovery

𝕏 PostBluesky