Author

Dewi P. I. Moonen

European Molecular Biology LaboratoryORCID 0000-0002-7113-698XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Judith B. ZauggiD· 2 shared Lars Michael SteinmetziD· 2 shared Andreas R. GschwindiD· 1 shared Annique ClaringbouldiD· 1 shared Armando Reyes‐PalomaresiD· 1 shared Aruna AyeriD· 1 shared Benedikt RauscheriD· 1 shared Britta VelteniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetics

Judith B. ZauggORCID

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2 papers

Recent·Most cited

Genome-scale mapping of variant, enhancer and gene function in primary human CD4+ T cells

Dewi P. I. Moonen, Annique Claringbould, Andreas R. Gschwind, Stefan Schrod, Jana M. Braunger, Claudia Feng, Benedikt Rauscher, Jia Yi, Shirley Z. Bi, Yves Matthess, Manuel Kaulich, Ricelle A Acob, Aruna Ayer, J Engreitz, Britta Velten, , Lars Michael Steinmetz

The paper maps variant, enhancer, and gene function in primary human CD4+ T cells by combining Perturb-seq of regulatory elements and genes, identifying CRE-gene pairs and linking variants to disease-related programs.

bioRxiv · Mar 11, 2026 · PreprintGenetics

Integration of genetic and epigenetic data pinpoints autoimmune specific remodelling of enhancer landscape in CD4+ T cells

Neha Daga, Nila H. Servaas, Kai E. Kisand, Dewi P. I. Moonen, Christian Arnold, Armando Reyes‐Palomares, Epp Kaleviste, Külli Kingo, Reet Kuuse, Katrin Ulst, Lars Michael Steinmetz, Pärt Peterson, Nikolina Nakić, Judith B. Zaugg

The paper integrates genetic and epigenetic data to identify autoimmune-specific enhancer dysregulation in CD4+ T cells and its role in disease pathogenesis.

bioRxiv · Jan 11, 2024 · PreprintGenomics