Armando Reyes‐Palomares

Tissue-specific transcriptomic responses to early Toxoplasma gondii infection in sheep during congenital toxoplasmosis

This study examines early transcriptomic responses to Toxoplasma gondii infection in pregnant sheep, identifying tissue-specific immune and stress pathways linked to fetal loss.

Single-cell multiomics reveals epigenetic rewiring of splenic memory B cells during murine malaria reinfection

The paper uses single-cell multiomics to study B cell changes in mice during malaria reinfection, finding shifts in memory B cell composition and epigenetic programs linked to rapid antibody production.

Cyclophosphamide chemotherapy induces early p53-directed cytotoxic gene expression changes in ovarian gonadotoxicity

This study examines the early transcriptomic changes in mouse ovaries after cyclophosphamide exposure, identifying p53-driven gene expression patterns linked to apoptosis and DNA damage.

Insights into Ancestral Diversity in Parkinsons Disease Risk: A Comparative Assessment of Polygenic Risk Scores

This study compares polygenic risk scores for Parkinson's disease across seven ancestries, finding varying predictive accuracy and highlighting the need for ancestry-specific models.

Purinergic Receptor P2Y13 Controls Activation and Mode of Division in Subependymal Adult Neural Stem Cells

This study identifies P2Y13 as a key regulator of NSC activation and division mode in the adult SEZ, distinguishing quiescent from activated NSCs and influencing self-renewal versus differentiation.

NeuroBooster Array: A Genome-Wide Genotyping Platform to Study Neurological Disorders Across Diverse Populations

The paper introduces the NeuroBooster Array, a genome-wide genotyping platform designed to study neurological disorders across diverse populations by capturing genetic variation and enabling imputation of disease-related variants.

Integration of genetic and epigenetic data pinpoints autoimmune specific remodelling of enhancer landscape in CD4+ T cells

The paper integrates genetic and epigenetic data to identify autoimmune-specific enhancer dysregulation in CD4+ T cells and its role in disease pathogenesis.

GRaNIE and GRaNPA: Inference and evaluation of enhancer-mediated gene regulatory networks applied to study macrophages

The paper introduces GRaNIE and GRaNPA, tools for inferring and evaluating enhancer-mediated gene regulatory networks in macrophages, identifying PURA as a regulator of pro-inflammatory polarization.

Quantification of differential transcription factor activity and multiomics-based classification into activators and repressors: diffTF

diffTF quantifies differential transcription factor activity and classifies TFs as activators or repressors using multi-omics data, identifying known and novel TFs in two case studies.