Author

Dianne Cox

Albert Einstein College of MedicineORCID 0000-0002-0591-9767Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jiufeng LiiD· 2 shared John C. McAuliffe· 2 shared John S. CondeelisiD· 2 shared Maja H. OktayiD· 2 shared Abigail Thomas· 1 shared Ben Z. StangeriD· 1 shared Camille L. DuraniD· 1 shared Chinmay R. Surve· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Jiufeng LiORCID

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3 papers

Recent·Most cited

A genetically encoded RhoG FRET biosensor reveals spatially compartmentalized RhoG-Rac1 signaling during cell protrusion

Maíra A. Lima, Abigail Thomas, Roshan Ravishankar, Rafael García‐Mata, Gaudenz M. Danuser, Veronika Miskolci, Dianne Cox, Louis Hodgson

The paper develops a FRET biosensor to visualize RhoG activity in live cells and shows its spatial relationship with Rac1 during protrusion.

bioRxiv · Aug 25, 2026 · PreprintCell Biology

Tie2 signaling in the tumor microenvironment orchestrates breast cancer cell dissemination through TMEM doorways

Camille L. Duran, Chinmay R. Surve, Prachiben P. Patel, Jack Hirsch, Jiufeng Li, Xianjun Ye, Nicole D. Barth, Xiaoming Chen, Suryansh Shukla, George S. Karagiannis, John C. McAuliffe, David Entenberg, Dianne Cox, John S. Condeelis, Maja H. Oktay

This study identifies macrophage Tie2 signaling as critical for TMEM doorway-mediated vascular permeability and metastatic dissemination in breast cancer.

bioRxiv · Apr 29, 2026 · PreprintCancer Biology

TMEM Doorway Mediated Metastasis in Pancreatic Ductal Adenocarcinoma by Tie2 Signaling

Érika Pereira Zambalde, Lina A. Ariyan, Francisco Puerta-Martinez, Yu Quin Zhu, Priyanka Patil, Nicole C. Panarelli, Jiufeng Li, Yookyung Jung, Christian Adkisson, Jakeb S. S. M. Petersen, Dianne Cox, Hava Gil-Henn, Robert J. Eddy, Ben Z. Stanger, David R. Entenberg, , John C. McAuliffe

This study identifies TMEM doorways as a mechanism for metastasis in PDAC, showing Tie2 macrophages facilitate intravasation and that targeting Tie2 improves survival in mouse models.

bioRxiv · Dec 9, 2025 · PreprintCancer Biology