Author

Fajun Yang

Albert Einstein College of MedicineORCID 0000-0002-7120-2449Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:statistical model· 4 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Alus M. XiaoliiD· 4 shared Jeffrey E. PessiniD· 4 shared Li Ping LiuiD· 3 shared Austin Landgraf· 2 shared Carolina EliscovichiD· 2 shared Irwin J. KurlandiD· 2 shared Junichi OkadaiD· 2 shared Kosaku ShinodaiD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMolecular Biology

Alus M. XiaoliORCID

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4 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 16, 2026

A novel subset of hepatocytes is simultaneously gluconeogenic and de novo lipogenic in the fed state and is naturally insulin resistant

Junichi Okada, Austin Landgraf, Maxwell Horton…·Jeffrey E. Pessin

DOI 10.64898/2026.03.09.710526

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Molecular BiologyJCI InsightPeer-reviewedFeb 26, 2026

TIGAR DEFICIENCY ENHANCES CARDIAC RESILIENCE THROUGH EPIGENETIC PROGRAMMING OF PARKIN EXPRESSION

Yan Tang, Stanislovas S. Jankauskas, Li Liu…·Jeffrey E. Pessin

This study shows TIGAR deficiency protects the heart through epigenetic regulation of Parkin, enhancing mitochondrial quality control and preventing cardiac damage.

1 citation

mousestatistical model

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Molecular BiologyNature MetabolismPeer-reviewedApr 25, 2025

Spatial hepatocyte plasticity of gluconeogenesis during the metabolic transitions between fed, fasted and starvation states

Junichi Okada, Austin Landgraf, Alus M. Xiaoli…·Jeffrey E. Pessin

The paper shows that gluconeogenic gene expression and activity in liver hepatocytes change spatially and temporally during feeding, fasting, and starvation states.

16 citationstop 1%

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GenomicsbioRxivPreprintNov 11, 2020

The regulation of liver gene expression by carbohydrates is mouse strain specific

Yuling Chi, Dou Yeon Youn, Alus M. Xiaoli…·Jeffrey E. Pessin

The paper shows that carbohydrate-induced gene expression changes in mouse liver vary by strain, with C57BL/6J showing greater sensitivity to sugar intake.

DOI 10.1101/2020.11.11.378497

mousebulk RNA-seq

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