Author

Austin Landgraf

Albert Einstein College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1

Frequent Co-Authors

Irwin J. KurlandiD· 3 shared Jeffrey E. PessiniD· 3 shared Junichi OkadaiD· 3 shared Kosaku ShinodaiD· 3 shared Li Ping LiuiD· 3 shared Maxwell Horton· 3 shared YUNPING QIUiD· 3 shared Alus M. XiaoliiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Irwin J. KurlandORCID

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3 papers

Recent·Most cited

A novel subset of hepatocytes is simultaneously gluconeogenic and de novo lipogenic in the fed state and is naturally insulin resistant

Junichi Okada, Austin Landgraf, Maxwell Horton, YUNPING QIU, Alus M. Xiaoli, Roberto A. Ribas, Li Ping Liu, Sofia V. Krylova, Hernando J. Olivos, Victor L. Schuster, Fajun Yang, Takeshi Saito, Ramon C. Sun, Meredith A. Hawkins, Gary J. Schwartz, , Jeffrey E. Pessin

bioRxiv · Mar 16, 2026 · PreprintMolecular Biology

Spatial hepatocyte plasticity of gluconeogenesis during the metabolic transitions between fed, fasted and starvation states

Junichi Okada, Austin Landgraf, Alus M. Xiaoli, Li Ping Liu, Maxwell Horton, Victor L. Schuster, Fajun Yang, Simone Sidoli, Yunping Qiu, Irwin J. Kurland, Carolina Eliscovich, Kosaku Shinoda, Jeffrey E. Pessin

The paper shows that gluconeogenic gene expression and activity in liver hepatocytes change spatially and temporally during feeding, fasting, and starvation states.

Nature Metabolism · Apr 25, 2025Peer-reviewedMolecular Biology

Widespread discordance between mRNA expression, protein abundance and de novo lipogenesis activity in hepatocytes during the fed-starvation transition

Austin Landgraf, Junichi Okada, Maxwell Horton, Li Ping Liu, Shoshana Solomon, Yunping Qiu, Irwin J. Kurland, Simone Sidoli, Jeffrey E. Pessin, Kosaku Shinoda

The paper examines mRNA, protein, and lipogenesis activity in hepatocytes during feeding and starvation, finding widespread discordance between mRNA and protein levels, especially in sex-biased genes and lipogenic pathways.

bioRxiv · Apr 15, 2025 · PreprintBioinformatics