Li Liu

Female-specific m6A remodeling in the liver correlates with post-transcriptional metabolic adaptation to high fat diet

The paper identifies female-specific m6A RNA methylation changes in mouse livers under high-fat diet that correlate with post-transcriptional metabolic adaptations and protein remodeling.

TIGAR DEFICIENCY ENHANCES CARDIAC RESILIENCE THROUGH EPIGENETIC PROGRAMMING OF PARKIN EXPRESSION

This study shows TIGAR deficiency protects the heart through epigenetic regulation of Parkin, enhancing mitochondrial quality control and preventing cardiac damage.

Transcriptional Heterogeneity Reveals a Synaptic Gene Program in Developing and Adult Human Oligodendrocyte Precursor Cells

The paper identifies a synaptic gene program in human oligodendrocyte precursor cells (OPCs) using single-cell RNA sequencing, revealing distinct embryonic and adult subsets with synaptic-related gene expression.

Longitudinal multimodal characterization of radiation dermatitis in the C57BL/6J mouse model

This study develops a longitudinal C57BL/6J mouse model of radiation dermatitis, revealing early molecular changes and distinct temporal signatures of inflammation, barrier dysfunction, and fibrosis.