Author
Kosaku Shinoda
Albert Einstein College of MedicineORCID 0000-0002-1928-0749Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links6 papers
Recent·Most cited
- GenomicsbioRxivPreprint
Longitudinal multimodal characterization of radiation dermatitis in the C57BL/6J mouse model
Jasmine H. Wong, Sharen Rivas, Li Liu…·Kosaku Shinoda
This study develops a longitudinal C57BL/6J mouse model of radiation dermatitis, revealing early molecular changes and distinct temporal signatures of inflammation, barrier dysfunction, and fibrosis.
DOI 10.1101/2025.11.08.687376 - Cancer BiologyNature CommunicationsPeer-reviewed
Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis
Jeremy Williams, Roman Camarda, Serghei Malkov…·Andrei Goga
The paper shows that gap junctions between breast cancer cells and adipocytes transfer cAMP, activating lipolysis in the tumor microenvironment to support tumor growth.
- Molecular BiologyNature MetabolismPeer-reviewed
Spatial hepatocyte plasticity of gluconeogenesis during the metabolic transitions between fed, fasted and starvation states
Junichi Okada, Austin Landgraf, Alus M. Xiaoli…·Jeffrey E. Pessin
The paper shows that gluconeogenic gene expression and activity in liver hepatocytes change spatially and temporally during feeding, fasting, and starvation states.
- BioinformaticsbioRxivPreprint
Widespread discordance between mRNA expression, protein abundance and de novo lipogenesis activity in hepatocytes during the fed-starvation transition
Austin Landgraf, Junichi Okada, Maxwell Horton…·Kosaku Shinoda
The paper examines mRNA, protein, and lipogenesis activity in hepatocytes during feeding and starvation, finding widespread discordance between mRNA and protein levels, especially in sex-biased genes and lipogenic pathways.
7 citations - BiochemistryACS Medicinal Chemistry LettersPeer-reviewed
In vivo-Active Soluble Epoxide Hydrolase-targeting PROTACs with Improved Potency and Stability
Keita Nakane, Christophe H.P. Morisseau, Presley D. Dowker-Key…·Seiya Kitamura
This paper develops next-generation sEH-targeting PROTACs with improved potency and stability, showing effective degradation in mouse tissues.
6 citations