Xiangbing Qi

This study identifies acepromazine as a compound that selectively degrades multimeric proteins via TRIM21 activation, offering a new strategy for targeting disease-related protein assemblies.

This paper improves the auxin-inducible degron system in fission yeast by optimizing the degron, inducer, and F-box protein, achieving inducible lethality for essential genes.

The paper identifies a brain circuit from the superior colliculus to the substantia nigra pars compacta that enhances appetitive locomotion during predatory hunting by modulating dopamine release.

This study shows STK11 is essential for ciliated cell differentiation by regulating MARK3 and ERK1/2 signaling in airway progenitors.