Author

Shivani Gupta

University of ZurichORCID 0000-0002-7156-5477Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Raffaella SantoroiD· 3 shared Cristiana BersaglieriiD· 2 shared Dominik Bär· 2 shared Jelena Kresoja‐RakiciD· 2 shared Mathieu RaingevaliD· 2 shared Chiara MungoiD· 1 shared Kaivalya WalavalkariD· 1 shared Luana Schaab· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersGenomics

Raffaella SantoroORCID

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3 papers

Recent·Most cited

Single-cell dynamics of genome-nucleolus interactions captured by nucleolar laser microdissection (NoLMseq)

Kaivalya Walavalkar, Shivani Gupta, Jelena Kresoja‐Rakic, Mathieu Raingeval, Chiara Mungo, Philip D. Rubin, Raffaella Santoro

This paper introduces NoLMseq, a method to map nucleolar-associated domains (NADs) in single cells, revealing their heterogeneity and response to nucleolar stress.

Nature Communications · Dec 17, 2025Peer-reviewedGenomics

NPM1 mediates genome-nucleolus interactions and the establishment of their repressive chromatin states

Shivani Gupta, Cristiana Bersaglieri, Dominik Bär, Mathieu Raingeval, Luana Schaab, Raffaella Santoro

This study identifies NPM1 as a mediator of nucleolar association with NADs and shows its role in establishing repressive H3K9me2 chromatin states at these domains.

bioRxiv · Jul 3, 2024 · PreprintMolecular Biology

Genome-wide maps of nucleolus interactions reveal distinct layers of repressive chromatin domains

Cristiana Bersaglieri, Jelena Kresoja‐Rakic, Shivani Gupta, Dominik Bär, Rostyslav Kuzyakiv, Martina Panatta, Raffaella Santoro

The paper develops a method to map nucleolar-associated domains (NADs) and shows they have distinct repressive chromatin states compared to nuclear lamina interactions.

Nature Communications · Mar 18, 2022Peer-reviewedGenomics