Author

Martina Panatta

University of ZurichORCID 0000-0002-8180-8380Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Cristiana BersaglieriiD· 2 shared Raffaella SantoroiD· 2 shared Adriano AguzziiD· 1 shared Alexander van der BourgiD· 1 shared Andreas R. HierlemanniD· 1 shared Dáša BohačiakováiD· 1 shared Deena M Leslie Pedrioli· 1 shared Dominik Bär· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersDevelopmental Biology

Cristiana BersaglieriORCID

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3 papers

Recent·Most cited

PRAMEL7/CUL2 axis regulates NuRD stability to establish ground-state pluripotency in embryonic stem cells

Meneka Rupasinghe, Cristiana Bersaglieri, Deena M Leslie Pedrioli, Patrick G. A. Pedrioli, Martina Panatta, Michael O. Hottiger, Paolo Cinelli, Raffaella Santoro

This study shows PRAMEL7 interacts with CUL2 to destabilize NuRD complex, promoting ground-state pluripotency in ESCs by reducing repressive chromatin regulation.

EMBO Reports · Feb 8, 2024Peer-reviewedDevelopmental Biology

Genome-wide maps of nucleolus interactions reveal distinct layers of repressive chromatin domains

Cristiana Bersaglieri, Jelena Kresoja‐Rakic, Shivani Gupta, Dominik Bär, Rostyslav Kuzyakiv, Martina Panatta, Raffaella Santoro

The paper develops a method to map nucleolar-associated domains (NADs) and shows they have distinct repressive chromatin states compared to nuclear lamina interactions.

Nature Communications · Mar 18, 2022Peer-reviewedGenomics

Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD

Marián Hruška-Plocháň, Katharina M. Betz, Silvia Ronchi, Vera I. Wiersma, Zuzanna Maniecka, Eva‐Maria Hock, Florent Laferrière, Sonu Sahadevan, Vanessa Hoop, Igor Delvendahl, Martina Panatta, Alexander van der Bourg, Dáša Bohačiaková, Karl Frontzek, Adriano Aguzzi, , Magdalini Polymenidou

The paper develops a human iPSC-derived neural model to study TDP-43 pathology, identifying NPTX2 misregulation as a key factor in ALS/FTLD neurotoxicity.

bioRxiv · Dec 8, 2021 · PreprintNeuroscience