3D Brain Vascular Niche Model Captures Invasive Behavior and Gene Signatures of Glioblastoma
Vivian K. Lee, Rut Tejero, Nathaniel Silvia, Anirudh Sattiraju, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Roland H. Friedel, Hongyan Zou, Guohao Dai
This paper develops a 3D brain vascular niche model to study GBM invasion and gene signatures, revealing glia-vascular contact influences transcriptional adaptation and poor prognosis.
Advanced Science · Jun 19, 2025Peer-reviewedBioengineering