Guohao Dai

This paper introduces NetDes, a method to infer gene regulatory networks and build dynamical models from single-cell gene expression data, showing its effectiveness in reconstructing cell state transitions.

This study develops an automated high-throughput heart-on-a-chip system using iPSC-derived cardiomyocytes and GCaMP6f for monitoring, showing a temperature-dependent decrease in beat rate.

This paper introduces a low-cost, demountable organ-on-chip platform using thermoplastics and a cut-and-assemble method, enabling high-resolution imaging and multi-layer tissue culture.

This paper develops a 3D brain vascular niche model to study GBM invasion and gene signatures, revealing glia-vascular contact influences transcriptional adaptation and poor prognosis.