MechanoMaST - a multimodal pipeline for spatially registering mechanical and transcriptomic tissue data
Linda Decker, Dmitrii Olisov, Nikolai Schleußner, Hendrik Wiethoff, Thomas Schmidt, Henrik Nienhueser, Thomas Moritz Pausch, Jan O. Korbel, Alba Diz-Muñoz
MechanoMaST integrates mechanical and transcriptomic data from tissue samples to enable spatial correlation with high accuracy, revealing a stiffness-related gene signature in colorectal cancer.
bioRxiv · Sep 30, 2026 · PreprintBiophysics