Ralf H. Adams

This study shows that vascular basement membrane laminins regulate cerebral microvessel functional zonation by modulating endothelial and mural cell identity and vascular permeability.

The paper shows that Wnt-dependent reprogramming of bone marrow niches drives fibrosis by activating osteolineage cells and altering hematopoietic support.

This study identifies adventitial leptin receptor-expressing fibroblasts as key contributors to cardiac fibrosis after myocardial infarction in mice and humans.

The paper uses a tissue-clearing protocol to spatially map BM-MSCs in human bones, revealing distinct microenvironment features in young and aged bones.

The paper identifies a specialized mesenteric lymphatic capillary network that bypasses mesenteric lymph nodes to directly transport peritoneal antigens into mediastinal lymph nodes.

The paper investigates age-related changes in endothelial cells of mice, identifying gene and chromatin alterations linked to increased intracerebral hemorrhage risk.

This study investigates the role of SRF in mural cells, showing its importance in pericyte migration, vessel patterning, and blood flow during development and disease.

The paper identifies a specialized fetal bone marrow niche regulated by arterial endothelial cells and Wnt2 signaling that supports hematopoietic stem and progenitor cell expansion.

This study shows that blood vessel regression in the brain reduces neuronal activity by impairing mitochondrial metabolism and glutamate production.

This study shows that loss of endothelial FSTL1 causes atrial and vein wall fibrosis through SMAD3 activation, leading to heart failure.

This study shows that Caspase-8 promotes angiogenesis in endothelial cells through a cell death-independent mechanism involving p38 MAPK activation and VE-cadherin destabilization.