Alba Diz-Muñoz

MechanoMaST integrates mechanical and transcriptomic data from tissue samples to enable spatial correlation with high accuracy, revealing a stiffness-related gene signature in colorectal cancer.

This study uses optogenetic control of actin crosslinker length to show how different crosslinker lengths affect cortical mechanics and drive cell polarization or delamination.

This study identifies moesin's role in osteoclast fusion and function, showing its impact on bone resorption and disease therapy.

This study shows that intercellular adhesion can drive collective cell migration through membrane tension and phospholipase D2 signaling, independent of cytoskeletal coupling.

The paper identifies biomechanical modules that govern larval shape diversity across six cnidarian species and shows how manipulating these modules can transform shapes between species.

This study shows PIEZO channels are essential for intestinal stem cell maintenance by sensing mechanical cues from their niche.

The paper shows how caging of MCA proteins can amplify changes in membrane viscosity and protein length, leading to symmetry breaking in cellular mechanics.

DeePiCt is a deep-learning framework for segmenting and localizing macromolecular complexes in cryo-electron tomograms, showing effectiveness in identifying low-abundance structures across species.

This study shows that mouse brain lipotypes develop in two stages, with cholesterol increasing postnatally, and that stem cell-derived neurons do not fully recapitulate this lipotype.

The paper identifies jag1a and her6/her9 as key components of a Notch GRN in zebrafish notochord cells and shows that stronger intracellular ligand-receptor interactions drive lateral inhibition patterning.