Author

Kasturi Mahadik

Centre National de la Recherche ScientifiqueORCID 0000-0002-7167-9028Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Carla Piqueras· 1 shared Charbel AlfeghalyiD· 1 shared Claire RougeulleiD· 1 shared Emmanuel CazottesiD· 1 shared Eva MoinardiD· 1 shared Gaël CasteliD· 1 shared Jean‐François OuimetteiD· 1 shared Jenna Lammers· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Carla Piqueras

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1 paper

Recent·Most cited

XIST dampens X chromosome activity in a SPEN-dependent manner during early human development

Charbel Alfeghaly, Gaël Castel, Emmanuel Cazottes, Madeleine Moscatelli, Eva Moinard, Miguel Casanova, Juliette Boni, Kasturi Mahadik, Jenna Lammers, Thomas Fréour, Louis Chauvière, Carla Piqueras, Ruben Boers, Joachim Boers, Joost H. Gribnau, , Claire Rougeulle

The paper shows XIST reduces X chromosome activity through SPEN-dependent mechanisms before XCI in human embryos, while XACT does not significantly affect XIST function.

Nature Structural & Molecular Biology · Jun 4, 2024Peer-reviewedMolecular Biology