Author

Madeleine Moscatelli

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Claire RougeulleiD· 3 shared Charbel AlfeghalyiD· 2 shared Emmanuel CazottesiD· 2 shared Gaël CasteliD· 2 shared Jean‐François OuimetteiD· 2 shared Joost H. GribnauiD· 2 shared Louis Chauvière· 2 shared Miguel CasanovaiD· 2 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Claire RougeulleORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

XIST Drives X-Chromosome Inactivation and Safeguards Female Extraembryonic Cells in Humans

Amitesh Panda, Leo Carrillo, Bradley Philip Balaton, Jeanne Brouillet, Solomon Nshemereirwe, Jarne Bonroy, Charbel Alfeghaly, Romina Facchinello, Sherif Khodeer, Ruben Boers, Gaël Castel, Charlie London, Emmanuel Cazottes, Madeleine Moscatelli, Raissa Songwa Tchinda, , Vincent Pasque

This study shows that XIST is required for XCI in human extraembryonic cells, which is essential for their survival and development.

bioRxiv · Nov 19, 2025 · PreprintDevelopmental Biology

XIST dampens X chromosome activity in a SPEN-dependent manner during early human development

Charbel Alfeghaly, Gaël Castel, Emmanuel Cazottes, Madeleine Moscatelli, Eva Moinard, Miguel Casanova, Juliette Boni, Kasturi Mahadik, Jenna Lammers, Thomas Fréour, Louis Chauvière, Carla Piqueras, Ruben Boers, Joachim Boers, Joost H. Gribnau, , Claire Rougeulle

The paper shows XIST reduces X chromosome activity through SPEN-dependent mechanisms before XCI in human embryos, while XACT does not significantly affect XIST function.

Nature Structural & Molecular Biology · Jun 4, 2024Peer-reviewedMolecular Biology

A primate-specific retroviral enhancer wires the XACT lncRNA into the core pluripotency network in human

Miguel Casanova, Madeleine Moscatelli, Louis Chauvière, Christophe Huret, Julia Samson, Tharvesh M. Liyakat Ali, Olga Rosspopoff, Claire Rougeulle

The paper identifies a primate-specific retroviral enhancer that integrates the XACT lncRNA into the human pluripotency network through evolutionary adaptation.

Nature Communications · Dec 11, 2019Peer-reviewedMolecular Biology