Author

Ward Develtere

Ghent UniversityORCID 0000-0002-7171-8031Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:CRISPR screen· 2 Research Focus:variant calling· 2 Organism:Arabidopsis· 1 Research Focus:perturbation response prediction· 1 Research Focus:software / tool· 1 Organism:zebrafish· 1

Frequent Co-Authors

Thomas B. JacobsiD· 3 shared Alexandra Peña Fernández· 1 shared Andrzej DrozdzeckiiD· 1 shared Camila GonzaleziD· 1 shared Chantal AndersiD· 1 shared Christian Damian LorenzoiD· 1 shared Christophe GaillochetiD· 1 shared David De Vleesschauwer· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersSynthetic Biology

Thomas B. JacobsORCID

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3 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintDec 19, 2023

Continual improvement of multiplex mutagenesis in Arabidopsis

Ward Develtere, Ward Decaestecker, Debbie Rombaut…·Thomas B. Jacobs

The paper tests multiple promoters and Cas9 NLS configurations in Arabidopsis to improve multiplex mutagenesis efficiency, finding the RPS5A promoter and double-BP NLS to be most effective.

1 citation

Arabidopsisexperimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintMay 11, 2022

Systematic optimization of Cas12a base editors in wheat and maize using the ITER platform

Christophe Gaillochet, Alexandra Peña Fernández, Vera Goossens…·Thomas B. Jacobs

The paper develops an optimized LbCas12a-ABE base editor in wheat and maize using the ITER platform, achieving 40% activity on a GFP reporter through iterative design.

4 citations

CRISPR screenexperimental assay

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Systems BiologybioRxivPreprintMay 2, 2022

BREEDIT: A novel multiplex genome editing strategy to improve complex quantitative traits in maize (Zea mays L.)

Christian Damian Lorenzo, Kévin Debray, Denia Herwegh…·Dirk Inzé

BREEDIT improves complex traits in maize by combining CRISPR/Cas9 gene editing with crossing schemes to generate mutants with enhanced growth characteristics.

3 citations

zebrafishCRISPR screen

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