Dynamic Localization of Leukemia Stem Cells via CXCL12 Regulates Leukemia Progression
Chen Wang, Yi Pan, Ruochen Dong…·Xunlei Kang
This study shows that the CXCL12 gradient, regulated by DPP4 and GPC3, determines leukemia stem cell (LSC) localization and behavior, influencing leukemia progression.