Cristina Ayuso

The paper shows that inactivating the NMD pathway suppresses the embryonic lethality of gsr-1 mutants in C. elegans by enabling the transsulfuration pathway to compensate for the loss of glutathione reductase function.

This paper introduces a C. elegans model of progeria by mutating baf-1 to mimic the human NGPS mutation, showing accelerated aging and altered gene expression.

The paper expands the FLP toolkit in C. elegans by adding new driver lines and a protein degradation system, enabling precise gene inactivation and transcriptomic profiling.

The paper develops an FLP-based toolkit for precise spatiotemporal control of gene expression in C. elegans, achieving high recombination efficiency in specific tissues.