Antonio Miranda‐Vizuete

Peroxiredoxin 6 limits mitochondrial peroxidation to prevent mitochondrial ER contact site assembly and inflammatory signalling following adaptive stress

This study shows PRDX6 limits mitochondrial lipid peroxidation under oxidative stress, preventing MERCS formation and inflammation in both myoblasts and C. elegans.

Mitochondrial redox homeostasis links organellar stress surveillance to germline and somatic integrity in Caenorhabditis elegans

This study shows that loss of mitochondrial glutathione reductase and thioredoxin reductase in C. elegans causes growth, fertility, and muscle defects, activates a constitutive UPRmt, and alters mitochondrial morphology.

PERK orchestrates MERCS formation and mitochondrial remodelling promoting physiological adaptations during adaptive UPR signalling

This study shows PERK promotes MERCS formation and mitochondrial remodelling during adaptive UPR signalling in myoblasts and C. elegans, enhancing physiological function.

The transsulfuration pathway suppresses the embryonic lethalphenotype of glutathione reductase mutants in Caenorhabditis elegans

The paper shows that inactivating the NMD pathway suppresses the embryonic lethality of gsr-1 mutants in C. elegans by enabling the transsulfuration pathway to compensate for the loss of glutathione reductase function.

Peroxiredoxin 2 Regulates DAF-16/FOXO Mediated Mitochondrial Remodelling in Response to Exercise that is Disrupted in Ageing

This study shows PRDX-2 regulates DAF-16/FOXO-mediated mitochondrial remodelling during exercise, which is disrupted in ageing in C. elegans.

A Tunable and Druggable Mechanism to Delay Forgetting of Olfactory Memories in C. elegans

This study shows that cold temperatures and lithium salt delay forgetting of olfactory memories in C. elegans by modulating membrane properties and the diacylglycerol pathway in specific neurons.

Peroxiredoxin 2 is required for the redox mediated adaptation to exercise

The paper shows that Peroxiredoxin 2 is essential for the beneficial adaptive response to exercise-induced oxidative stress in C. elegans.

Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation

This study shows that loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation in C. elegans and other organisms.

Epicatechin modulates stress-resistance in C. elegans via Insulin/IGF-1 signaling pathway

This study shows that epicatechin enhances stress resistance in C. elegans by modulating the insulin/IGF-1 signaling pathway.