Author

Long Xie

Siemens (United States)ORCID 0000-0002-7184-7028Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:human· 6 Assay:imaging· 5 Approach:statistical model· 4 Research Focus:benchmarking· 2 Research Focus:spatial domain detection· 2 Research Focus:clustering· 1 Research Focus:database / resource· 1 Approach:deep learning· 1

Frequent Co-Authors

David A. WolkiD· 6 shared Paul A. YushkevichiD· 5 shared Sandhitsu R. DasiD· 5 shared John A. DetreiD· 4 shared Karthik Prabhakaran· 4 shared Laura E. M. WisseiD· 4 shared Matthew Dylan TisdalliD· 4 shared Carlos de la Rosa‐PrietoiD· 3 shared

Activity by Year

2019-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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6 shared papersNeuroscience

David A. WolkORCID

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Author profile →

6 papers

Recent·Most cited

Characterization of hippocampal subfields using histology-based annotated postmortem MRI: Lessons for in vivo segmentation II

HL Tucker, Bradley G. Karat, AT De Ruiter, Dana M. Parker, Sydney Lim, AE Denning, Ranjit Ittyerah, Lisa M Levorse, Winifred Trotman, Alejandra Bahena, Eunice P. Chung, Karthik Prabhakaran, Madigan L. Bedard, Daniel T. Ohm, Long Xie, , LEM Wisse

The paper characterizes hippocampal subfield border variability using postmortem MRI and histology, finding consistent subfield appearance/disappearance orders and no clear diagnosis-related differences.

bioRxiv · Nov 21, 2025 · PreprintNeuroscience

Automatic segmentation of medial temporal lobe subregions in multi-scanner, multi-modality MRI of variable quality

Yue Li, Long Xie, Pulkit Khandelwal, Laura E. M. Wisse, Christopher A. Brown, Karthik Prabhakaran, Matthew Dylan Tisdall, Dawn J. Mechanic-Hamilton, John A. Detre, Sandhitsu R. Das, David A. Wolk, Paul A. Yushkevich

This paper develops a multi-modality MRI segmentation model to improve robustness of medial temporal lobe subregion segmentation in poor-quality images.

Hippocampus · Oct 7, 2025Peer-reviewedBioengineering

Developing an anatomically valid segmentation protocol for anterior regions of the medial temporal lobe for neurodegenerative diseases

Niyousha Sadeghpour, Sydney Lim, Anika Wuestefeld, Amanda E Denning, Ranjit Ittyerah, Winifred Trotman, Eunice P. Chung, Shokufeh Sadaghiani, Karthik Prabhakaran, Madigan L. Bedard, Daniel T. Ohm, Emilio Artacho‐Pérula, Maria Mercedes Iniguez de Onzono Martin, Mónica Muñoz, Francisco Javier Molina Romero, , Laura E.M. Wisse

The paper develops a segmentation protocol for anterior medial temporal lobe regions and integrates it into an automated approach to improve imaging biomarkers for neurodegenerative diseases.

Hippocampus · Jul 30, 2025Peer-reviewedNeuroscience

3D Mapping of Neurofibrillary Tangle Burden in the Human Medial Temporal Lobe

Paul A. Yushkevich, Mónica Muñoz, Maria Mercedes Iniguez de Onzono Martin, Ranjit Ittyerah, Sydney Lim, Sadhana Ravikumar, Madigan L. Bedard, Stephen Pickup, Weixia Liu, Jiancong Wang, Alex Ling Yu Hung, Jade Lasserve, Nicolas Vergnet, Long Xie, Mengjin Dong, , Ricardo Insausti

This study creates 3D maps of neurofibrillary tangle burden in the human medial temporal lobe using ex vivo MRI and dense histology, revealing variation along the anterior-posterior axis and widespread NFT distribution.

bioRxiv · Jan 15, 2021 · PreprintNeuroscience

Neural and behavioral correlates of episodic memory are associated with temporal discounting in older adults

Karolina Maria Lempert, Dawn J. Mechanic-Hamilton, Long Xie, Laura E.M. Wisse, Robin de Florès, Jieqiong Wang, Sandhitsu R. Das, Paul A. Yushkevich, David A. Wolk, Joseph W. Kable

The paper examines the link between episodic memory and temporal discounting in older adults, finding that better memory correlates with less discounting of delayed rewards.

Neuropsychologia · Jul 1, 2020Peer-reviewedNeuroscience

Preserved global cerebral blood flow accounts for youthful processing speed in older adults

Fan Nils Yang, Long Xie, Olga Galli, John A. Detre, David A. Wolk, Hengyi Rao

The paper investigates the relationship between global cerebral blood flow and processing speed in older adults, finding that preserved global CBF correlates with youthful processing speed.

bioRxiv · Jun 10, 2019 · PreprintNeuroscience