Author

Phillip Wulfridge

Johns Hopkins UniversityORCID 0000-0002-7195-6814Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Andrew P. FeinbergiD· 2 shared Kasper D. HanseniD· 2 shared Adam DavidovichiD· 1 shared Adrian IdriziiD· 1 shared Anna C. SalvadoriD· 1 shared Ben LangmeadiD· 1 shared Brian J. BennettiD· 1 shared David W. ThreadgilliD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenetics

Andrew P. FeinbergORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintApr 25, 2023

Precision pharmacological reversal of genotype-specific diet-induced metabolic syndrome in mice informed by transcriptional regulation

Phillip Wulfridge, Adam Davidovich, Anna C. Salvador…·Andrew P. Feinberg

The paper uses mouse models to study diet-induced metabolic syndrome, identifies strain-specific transcriptional and epigenomic changes, and tests genotype-targeted pharmacological interventions.

DOI 10.1101/2023.04.25.538156

mousebulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintJan 22, 2021

BisMapR: a strand-specific, nuclease-based method for genome-wide R-loop detection

Phillip Wulfridge, Kavitha Sarma

BisMapR is a strand-specific, nuclease-based method for genome-wide R-loop detection, revealing new features of active enhancers and promoter R-loop behavior.

2 citations

humanDNA methylation

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GenomicsNucleic Acids ResearchPeer-reviewedJul 25, 2019

Analyzing whole genome bisulfite sequencing data from highly divergent genotypes

Phillip Wulfridge, Ben Langmead, Andrew P. Feinberg, Kasper D. Hansen

The paper analyzes whole-genome bisulfite sequencing data from two divergent mouse strains to address challenges in differential methylation analysis due to strain-specific CpG sites.

35 citations

mousewhole-genome sequencing

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