Single-cell transcriptional landscape of muscle-derived stem/progenitor cells reveals hallmarks of aging and rejuvenation
Kavitha Mukund, Seth D. Thompson, Chelsea L. Rugel, Kamil K. Gebis, Richard L. Lieber, Jeffrey N. Savas, Shankar Subramaniam, Mitra Lavasani
The paper profiles murine muscle-derived stem/progenitor cells across age groups using single-cell transcriptomics and proteomics, revealing a transcriptional continuum of maturation and aging-related changes.
bioRxiv · May 1, 2026 · PreprintCell Biology