Author

Björn van Sambeek

University Medical Center UtrechtORCID 0000-0002-7230-8755Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alexander van OudenaardeniD· 1 shared Karen B. van den Anker· 1 shared Maria J. Rodríguez ColmaniD· 1 shared Marjolein J. Vliem· 1 shared Martijn GloerichiD· 1 shared Mirjam C. van der NetiD· 1 shared Ronja M. HoutekameriD· 1 shared Rutger N.U. KokiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

Alexander van OudenaardenORCID

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1 paper

Recent·Most cited

Mechanical strain of the intestinal epithelium directs absorptive lineage maturation

Ronja M. Houtekamer, Björn van Sambeek, Karen B. van den Anker, Marjolein J. Vliem, Rutger N.U. Kok, Mirjam C. van der Net, Maria J. Rodríguez Colman, Alexander van Oudenaarden, Martijn Gloerich

This study shows that mechanical strain on intestinal organoids reduces the maturity of absorptive lineage cells by expanding early-stage enterocytes and downregulating maturation programs.

bioRxiv · Jul 9, 2026 · PreprintCell Biology