Maria J. Rodríguez Colman

NuclearIDTracker uses nuclear phenotypic signatures to classify intestinal cell types and track lineage dynamics without fluorescent reporters.

This study shows that mechanical strain on intestinal organoids reduces the maturity of absorptive lineage cells by expanding early-stage enterocytes and downregulating maturation programs.

This study shows WNT7B drives pancreatic cancer subtype switching and progression by promoting a basal-like state and influencing cell communication within tumors.

The paper develops an NMR-based method to quantify global protein arginine methylation levels across various biological samples and demonstrates its prevalence and modulation in health and disease.

The paper identifies a FOXO-dependent mechanism that restricts proliferation of cells with mild replication stress by promoting premature activation of APC/CCDH1.