Cell BiologybioRxivPreprint
Mechanical strain of the intestinal epithelium directs absorptive lineage maturation
Ronja M. Houtekamer, Björn van Sambeek, Karen B. van den Anker…·Martijn Gloerich
This study shows that mechanical strain on intestinal organoids reduces the maturity of absorptive lineage cells by expanding early-stage enterocytes and downregulating maturation programs.
DOI 10.64898/2026.07.08.737211