Jag1 modulates an oscillatory Dll1-Notch-Hes1 signaling module to coordinate growth and fate of pancreatic progenitors
Philip Allan Seymour, Caitlin Collin, Anuska la Rosa Egeskov-Madsen, Mette Christine Jørgensen, Hiromi Shimojo, Itaru Imayoshi, Kristian Honnens de Lichtenberg, Raphael Kopan, Ryoichiro Kageyama, Palle Serup
This study shows Jag1 modulates oscillatory Dll1-Notch-Hes1 signaling in pancreatic progenitors to coordinate their growth and fate, with Jag1 also specifying most bipotent progenitors.
Developmental Cell · Feb 13, 2020Peer-reviewedDevelopmental Biology