Multimodal mapping of systemic inflammation and immunity acrossthe spectrum of CFTR dysfunction
Leander Jonckheere, Simon Jan Tavernier, Iris Janssens, Yannick Vande Weygaerde, Heidi Schaballie, Petra Schelstraete, Stéphanie Van Biervliet, Robin Browaeys, Niels Vandamme, Evi Duthoo, Sebastian Riemann, Tania Maes, Victor Bosteels, Filomeen Haerynck, Bart N. Lambrecht, , Eva Van Braeckel
The paper examines systemic immune changes across the CFTR dysfunction spectrum using single-cell immune profiling in pwCF, carriers, and non-carriers, revealing immune signatures linked to CFTR function.
bioRxiv · Jun 10, 2026 · PreprintImmunology