Ankita Sharma

Conserved Roles of Sp1 in Zebrafish Development and Early Organogenesis

This study characterizes the expression profile and establishes the conserved role of SP1 in specific processes during zebrafish development, which were previously unreported.

SP1 amplifies the effects of cellular proliferation via the Wnt/β-catenin pathway in colon development and cancer

This study shows that SP1 enhances Wnt/β-catenin pathway effects on cell proliferation in colon development and cancer, with conserved roles in both contexts.

Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis

The paper investigates the role of Satb2 in regulating zygotic genome activation and developmental transitions during vertebrate embryogenesis, showing distinct maternal and zygotic functions.

A novel cis regulatory element regulates human XIST in CTCF-dependent manner

The paper identifies a novel cis regulatory element in human XIST that is regulated by CTCF and YY1 during X chromosome inactivation.

Regulation of transcription factor SP1 by β-catenin destruction complex modulates Wnt response

This study identifies a direct link between SP1 and β-catenin in the Wnt signaling pathway, showing their mutual stabilization and role in target gene expression.