Author

Rami Yair Tshuva

Weizmann Institute of ScienceORCID 0000-0002-7032-2107Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Bidisha BhattacharyaiD· 2 shared Miri Danan-GottholdiD· 2 shared Orly ReineriD· 2 shared Tsviya OlenderiD· 2 shared Aditya KshirsagariD· 1 shared Bruria Ben ZeeviD· 1 shared Corey C. HarwelliD· 1 shared Jeyoon Bok· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersDevelopmental Biology

Bidisha BhattacharyaORCID

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2 papers

Recent·Most cited

Neural Progenitors as a Novel Pathogenic Mechanism in Microcephaly

Rami Yair Tshuva, Jeyoon Bok, Mio Nonaka, Xufeng Xue, Bidisha Bhattacharya, Aditya Kshirsagar, Tsviya Olender, Miri Danan-Gotthold, Tamar Sapir, Jianping Fu, Orly Reiner

This study shows that NDE1 loss disrupts neural progenitor identity and forebrain patterning, leading to microcephaly through altered ERK signaling and regional identity shifts.

bioRxiv · Aug 12, 2025 · PreprintDevelopmental Biology

PRDM16 co-operates with LHX2 to shape the human brain

Varun Suresh, Bidisha Bhattacharya, Rami Yair Tshuva, Miri Danan-Gotthold, Tsviya Olender, Mahima Bose, Saurabh J. Pradhan, Bruria Ben Zeev, Richard S. Smith, Shubha Tole, Sanjeev Galande, Corey C. Harwell, José‐Manuel Baizabal, Orly Reiner

The paper investigates PRDM16's role in human brain development by analyzing a patient mutation and cortical organoids, revealing its collaboration with LHX2 in gene regulation.

Oxford Open Neuroscience · Jan 1, 2024Peer-reviewedDevelopmental Biology